(Mujadila) 58 : 5
إِنَّ الَّذِينَ يُحَادُّونَ اللَّهَ وَرَسُولَهُ كُبِتُوا كَمَا كُبِتَ الَّذِينَ مِنْ قَبْلِهِمْ ۚ وَقَدْ أَنْزَلْنَا آيَاتٍ بَيِّنَاتٍ ۚ وَلِلْكَافِرِينَ عَذَابٌ مُهِينٌ

Indeed those who are opposing Allah and His Messengers will be humiliated just like those who before them were humiliated; and surely We have sent down clear verses, while for the disbelievers have heinous punishment.

Today ‘To oppose Allah and His Messenger’ means to oppose Adhikr which is Lord’s Speech to His entire mankind. The disbelievers who are compared to the dog in verse 7: 176 which won’t change its attitude whether attacked or not, to the donkey in verse 62: 5 bearing the burden which doesn’t know what it bears, who are mentioned as Mujirim in verse  7: 40, the worst creatures among thousand communities of Lord’s creatures in verse 8: 22, and the worst creatures among the four hundred communities of Lord’s creatures in the land in verse 98: 6 are destroying the universe by hiding and rejecting Adhikr-the Balance and Trust to keep the universe in its equilibrium, so that heinous punishment is kept prepared for them in the Hereafter. These Fujjar are reading the verses 4: 150-151 which say that they are the true disbelievers, and for them heinous punishment is kept prepared.  See explanation 31: 5-6; 34: 19-20; and 48: 6, 24-25.